Cardinal
Amtrak's three-days-a-week train between New York and Chicago by way of Washington, Charlottesville, West Virginia's river gorges, Cincinnati and Indianapolis. The schedule shows roughly 27½ to 28¾ hours.
Dates and tickets
Amtrak
Three departures a week in each direction, all year
27 hours 30 minutes to 28 hours 45 minutes
Last checked Nov 12, 2026
See dates and book on Amtrak's site
Leaves from New York Moynihan Train Hall at Penn Station, Chicago Union Station. Ends at Chicago (westbound) or New York (eastbound).